Record Information |
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Version | 1.0 |
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Creation Date | 2016-09-30 22:18:54 UTC |
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Update Date | 2020-06-04 20:51:07 UTC |
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MCDB ID | BMDB0000044 |
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Secondary Accession Numbers | - BMDB00044
- BMDB0014273
- BMDB14273
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Metabolite Identification |
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Common Name | Ascorbic acid |
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Description | Ascorbic acid, also known as ascorbate, belongs to the class of organic compounds known as furanones. Furanones are compounds containing a furan ring bearing a ketone group. Ascorbic acid is possibly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Dopamine and ascorbic acid can be converted into norepinephrine and dehydroascorbic acid through the action of the enzyme dopamine beta-hydroxylase. In cattle, ascorbic acid is involved in the metabolic pathway called the tyrosine metabolism pathway. |
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Structure | |
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Synonyms | Value | Source |
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Acide ascorbique | ChEBI | Acido ascorbico | ChEBI | Acidum ascorbicum | ChEBI | Acidum ascorbinicum | ChEBI | Ascoltin | ChEBI | Ascorbicap | ChEBI | Ascorbinsaeure | ChEBI | e 300 | ChEBI | e-300 | ChEBI | e300 | ChEBI | L-(+)-Ascorbic acid | ChEBI | L-Ascorbate | ChEBI | Vitamin C | ChEBI | Monodehydroascorbate radical | Kegg | Ascorbate radical | Kegg | Semidehydroascorbic acid | Kegg | ASCOR | Kegg | L-(+)-Ascorbate | Generator | L-Ascorbic acid | Generator | Monodehydroascorbic acid radical | Generator | Ascorbic acid radical | Generator | Semidehydroascorbate | Generator | Ascorbate | Generator | (+)-Ascorbate | HMDB | (+)-Ascorbic acid | HMDB | (+)-Sodium L-ascorbate | HMDB | 3-keto-L-Gulofuranolactone | HMDB | 3-oxo-L-Gulofuranolactone | HMDB | Adenex | HMDB | Allercorb | HMDB | Antiscorbic vitamin | HMDB | Antiscorbutic vitamin | HMDB | arco-Cee | HMDB | Ascor-b.i.d. | HMDB | Ascorb | HMDB | Ascorbajen | HMDB | Ascorbicab | HMDB | Ascorbicin | HMDB | Ascorbin | HMDB | Ascorbutina | HMDB | Ascorin | HMDB | Ascorteal | HMDB | Ascorvit | HMDB | C-Level | HMDB | C-Long | HMDB | C-Quin | HMDB | C-Span | HMDB | C-Vimin | HMDB | Cantan | HMDB | Cantaxin | HMDB | Catavin C | HMDB | Ce lent | HMDB | Ce-mi-lin | HMDB | Ce-vi-sol | HMDB | Cebicure | HMDB | Cebid | HMDB | Cebion | HMDB | Cebione | HMDB | Cecon | HMDB | Cee-caps TD | HMDB | Cee-vite | HMDB | Cegiolan | HMDB | Ceglion | HMDB | Ceklin | HMDB | Celaskon | HMDB | Celin | HMDB | Cell C | HMDB | Cemagyl | HMDB | Cemill | HMDB | Cenetone | HMDB | Cenolate | HMDB | Cereon | HMDB | Cergona | HMDB | Cescorbat | HMDB | Cetamid | HMDB | Cetane | HMDB | Cetane-caps TC | HMDB | Cetane-caps TD | HMDB | Cetebe | HMDB | Cetemican | HMDB | Cevalin | HMDB | Cevatine | HMDB | Cevex | HMDB | Cevi-bid | HMDB | Cevimin | HMDB | Cevital | HMDB | Cevitamate | HMDB | Cevitamic acid | HMDB | Cevitamin | HMDB | Cevitan | HMDB | Cevitex | HMDB | Cewin | HMDB | Chewcee | HMDB | Ciamin | HMDB | Cipca | HMDB | Citriscorb | HMDB | Citrovit | HMDB | Colascor | HMDB | Concemin | HMDB | Davitamon C | HMDB | Dora-C-500 | HMDB | Duoscorb | HMDB | Ferrous ascorbate | HMDB, MeSH | gamma-Lactone L-threo-hex-2-enonate | HMDB | gamma-Lactone L-threo-hex-2-enonic acid | HMDB | HiCee | HMDB | Hybrin | HMDB, MeSH | ido-C | HMDB | Juvamine | HMDB | Kangbingfeng | HMDB | Kyselina askorbova | HMDB | L(+)-Ascorbate | HMDB | L(+)-Ascorbic acid | HMDB | L-3-Ketothreohexuronic acid lactone | HMDB | L-Lyxoascorbate | HMDB | L-Lyxoascorbic acid | HMDB | L-threo-Ascorbic acid | HMDB | L-Xyloascorbate | HMDB | L-Xyloascorbic acid | HMDB | Laroscorbine | HMDB | Lemascorb | HMDB | Liqui-cee | HMDB | Meri-c | HMDB | Natrascorb | HMDB | Natrascorb injectable | HMDB | Planavit C | HMDB | Proscorbin | HMDB | Redoxon | HMDB | Ribena | HMDB | Ronotec 100 | HMDB | Rontex 100 | HMDB | Roscorbic | HMDB | Rovimix C | HMDB | Scorbacid | HMDB | Scorbu C | HMDB | Scorbu-C | HMDB | Secorbate | HMDB | Sodascorbate | HMDB | Suncoat VC 40 | HMDB | Testascorbic | HMDB | VASC | HMDB | Vicelat | HMDB | Vicin | HMDB | Vicomin C | HMDB | Viforcit | HMDB | Viscorin | HMDB | Viscorin 100m | HMDB | Vitace | HMDB | Vitacee | HMDB | Vitacimin | HMDB | Vitacin | HMDB | Vitamisin | HMDB | Vitascorbol | HMDB | Xitix | HMDB | L Ascorbic acid | MeSH, HMDB | Acid, ascorbic | MeSH, HMDB | Ascorbate, ferrous | MeSH, HMDB | Ascorbate, sodium | MeSH, HMDB | Magnesium ascorbate | MeSH, HMDB | Magnesium ascorbicum | MeSH, HMDB | Magnesium di-L-ascorbate | MeSH, HMDB | Di-L-ascorbate, magnesium | MeSH, HMDB | Ascorbic acid, monosodium salt | MeSH, HMDB | Magnesium di L ascorbate | MeSH, HMDB | Magnorbin | MeSH, HMDB | Sodium ascorbate | MeSH, HMDB | Acid, L-ascorbic | MeSH, HMDB | Ascorbate, magnesium | MeSH, HMDB | ASCORBIC ACID | ChEBI |
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Chemical Formula | C6H8O6 |
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Average Molecular Weight | 176.1241 |
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Monoisotopic Molecular Weight | 176.032087988 |
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IUPAC Name | Not Available |
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Traditional Name | Not Available |
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CAS Registry Number | Not Available |
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SMILES | Not Available |
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InChI Identifier | InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1 |
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InChI Key | CIWBSHSKHKDKBQ-JLAZNSOCSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom. |
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Kingdom | Organic compounds |
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Super Class | Organoheterocyclic compounds |
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Class | Dihydrofurans |
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Sub Class | Furanones |
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Direct Parent | Butenolides |
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Alternative Parents | |
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Substituents | - 2-furanone
- Vinylogous acid
- Alpha,beta-unsaturated carboxylic ester
- Enoate ester
- 1,2-diol
- Carboxylic acid ester
- Enediol
- Secondary alcohol
- Lactone
- Carboxylic acid derivative
- Oxacycle
- Monocarboxylic acid or derivatives
- Alcohol
- Hydrocarbon derivative
- Organic oxygen compound
- Carbonyl group
- Organic oxide
- Primary alcohol
- Organooxygen compound
- Aliphatic heteromonocyclic compound
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Molecular Framework | Aliphatic heteromonocyclic compounds |
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External Descriptors | |
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Physical Properties |
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State | Solid |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Predicted Properties | Not Available |
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Spectra |
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Concentrations |
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Detected and Quantified | 22.71 +/- 1.42 uM | | | details | Detected and Quantified | 34 +/- 1.7 uM | | | details | Detected and Quantified | 153 uM | | | details | Detected and Quantified | 51 uM | | | details | Detected and Quantified | 51 uM | | | details | Detected and Quantified | 57 uM | | | details | Detected and Quantified | 51 uM | | | details | Detected and Quantified | 68 uM | | | details | Detected and Quantified | 57 uM | | | details | Detected and Quantified | 63 uM | | | details | Detected and Quantified | 57 uM | | | details | Detected and Quantified | 74 uM | | | details | Detected and Quantified | 74 uM | | | details | Detected and Quantified | 85 uM | | | details | Detected and Quantified | 63 uM | | | details | Detected and Quantified | 57 uM | | | details | Detected and Quantified | 63 uM | | | details | Detected and Quantified | 11 uM | | | details | Detected and Quantified | 11 uM | | | details | Detected and Quantified | 74 uM | | | details | Detected and Quantified | 74 uM | | | details | Detected and Quantified | 74 uM | | | details | Detected and Quantified | 68 uM | | | details | Detected and Quantified | 68 uM | | | details | Detected and Quantified | 68 uM | | | details | Detected and Quantified | 53 uM | | | details | Detected and Quantified | 53 - 56 uM | | | details | Detected and Quantified | 62 - 129 uM | | | details | Detected and Quantified | 34.7 +/- 0.2 uM | | | details | Detected and Quantified | 39 +/- 1 uM | | | details | Detected and Quantified | 34.0 +/- 0.3 uM | | | details | Detected and Quantified | 8.2 +/- 0.3 uM | | | details |
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External Links |
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HMDB ID | HMDB0014273 |
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DrugBank ID | DB00126 |
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Phenol Explorer Compound ID | Not Available |
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FoodDB ID | FDB001224 |
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KNApSAcK ID | C00001179 |
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Chemspider ID | 10189562 |
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KEGG Compound ID | C01041 |
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BioCyc ID | ASCORBATE |
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BiGG ID | Not Available |
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Wikipedia Link | Ascorbic_Acid |
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METLIN ID | Not Available |
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PubChem Compound | Not Available |
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PDB ID | Not Available |
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ChEBI ID | 29073 |
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References |
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Synthesis Reference | Not Available |
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Material Safety Data Sheet (MSDS) | Download (PDF) |
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General References | - Bilic N: Assay for both ascorbic and dehydroascorbic acid in dairy foods by high-performance liquid chromatography using precolumn derivatization with methoxy- and ethoxy-1,2-phenylenediamine. J Chromatogr. 1991 May 10;543(2):367-74. [PubMed:1880195 ]
- Gaucheron F: Milk and dairy products: a unique micronutrient combination. J Am Coll Nutr. 2011 Oct;30(5 Suppl 1):400S-9S. [PubMed:22081685 ]
- Weiss WP, Hogan JS, Smith KL: Changes in vitamin C concentrations in plasma and milk from dairy cows after an intramammary infusion of Escherichia coli. J Dairy Sci. 2004 Jan;87(1):32-7. doi: 10.3168/jds.S0022-0302(04)73138-0. [PubMed:14765807 ]
- Ingela Andersson, R. Öste (1994). Int. Dairy Journal 4 (1994) 161-172. International Dairy Journal.
- A. Foroutan et al. (2019). A. Foroutan et al. The Chemical Composition of Commercial Cow's Milk (in preparation). Journal of Agricultural and Food Chemistry.
- Park, Y. W; Juárez, Manuela ; Ramos, M.; Haenlein, G. F. W. (2007). Park, Y. W; Juárez, Manuela ; Ramos, M.; Haenlein, G. F. W.. Physico-chemical characteristics of goat and sheep milk. Small Ruminant Res.(2007) 68:88-113 doi: 10.1016/j.smallrumres.2006.09.013. Small Ruminant Research.
- USDA Food Composition Databases [Link]
- Fooddata+, The Technical University of Denmark (DTU) [Link]
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